Side effects of Sorafenib March 1 2007

This week my blood pressure is 140 over 77

Here is an update on the side effect of the Sorafenib trial.

I started the drug on 2/14/2007 400 mg twice daily.

The next day I notice a bad taste in my mouth that I could not get rid of. My tongue became sensitive. Eventually my gum became sensitive and tender with some minor bleeding.

Around the fourth day my scalp became tender to touch and had a burning sensation. I have noticed unusual bumps on my head. After a week my hair has been falling out more that usual.

One week on the drug my hands and feet began to hurt. It is now difficult to wear my shoes and i have some limitation of what I can do with my hands. I cannot open jars or lids. Any task that include small details are difficult for me to do.

Ten day after the start of the drug I developed a drug rash. This started on my arms, it has now spread all over my body. The rash is hot and at times itchy. I am using Benadryl.

I have had a low grade fever less than 100 degrees.